PerioTrap Pharmaceuticals GmbH
Precision Oral Care – Powered by the Microbiome
Our patented pathoblocker technology selectively targets harmful bacteria while preserving the protective oral flora.
Ausgründung aus dem
Unternehmensprofil
Health & Life Science
#Oral Health
#Biotech
Gründung:
23.01.2019
Geschäftszweck: Development of oral care and therapeutic solutions to reduce the global burden of periodontitis.
Gründer:
Mirko Buchholz
Pierre Tangermann
https://periotrap.com/
Problem
Periodontitis is one of the most prevalent chronic diseases worldwide, affecting over 750 million people.It is a leading cause of tooth loss and is strongly linked to systemic conditions such as diabetes, cardiovascular disease, and Alzheimer’s. Professional treatments are invasive, costly, and often fail to prevent recurrence. Current oral care products provide little relief: generic formulations, including broad antimicrobials, require continuous use, disrupt the oral microbiome, and frequently cause irritation over time. Yet they still fail to halt disease progression at the desired pace. As a result, patients remain trapped in a cycle of progressive tissue damage and chronic inflammation.
Lösung
PerioTrap provides a precision approach to gum health.Our patented small-molecule inhibitor blocks P. gingivalis, the “keystone” bacterium that drives periodontitis by destabilizing the oral microbiome and triggering chronic inflammation. By neutralizing this pathogen, we address the root cause of disease while preserving beneficial bacteria. This breaks the cycle of tissue destruction that current treatments fail to stop. The technology has been formulated into a dental gel and toothpaste that are cosmetic-grade, professionally endorsed, and already available on the market. With strong scientific validation, mucoadhesive delivery for longer residence time, and a scalable platform, PerioTrap bridges the gap between cosmetic oral care and therapeutic benefit, with future potential in medical, veterinary, and global markets.
Produkt
Our first products include a toothpaste for daily use and a professional dental gel recommended by dentists after cleaning. Both are designed to integrate seamlessly into established oral-care routines while setting a new standard in microbiome-friendly gum protection. With this platform, PerioTrap aims to become the “new fluoride for gum health,” expanding into additional product formats and markets in the future.Alleinstellung
PerioTrap is the first oral-care platform that uses precision pathoblocker technology to selectively inhibit periodontal pathogens such as P. gingivalis while preserving the protective oral microbiome. This enables effective gum protection without collateral damage – combining clinical relevance, microbiome safety, and everyday usability in formats like toothpaste and dental gel.Geschäftsmodell
PerioTrap generates revenue through premium oral-care products such as toothpaste and dental gel, sold via pharmacies, online channels, and dental professionals. Our “professional pull” strategy ensures dentist recommendation as a key driver of consumer adoption. Beyond direct product sales, we leverage partnerships with leading dental companies for distribution and co-branding, enabling faster market access. Long-term growth is driven by our pathoblocker platform, which can expand into new formats (mouthwash, gum, veterinary care, pharmaceuticals) and geographies. This dual model of product sales and scalable licensing positions PerioTrap for sustainable profitability with attractive margins.Traction / Highlights
- First products launched: Dental gel and toothpaste, compliant with EU cosmetics regulation, already available on the market
- Professional endorsement: Strategic partnership with EMS (Guided Biofilm Therapy) and KOL network
- Growing sales channels: Pharmacies, B2B online shops, and dental practices across multiple EU countries
- Strong IP position: Patented small-molecule inhibitor platform targeting P. gingivalis
- Scientific validation: Multi-species biofilm assays and long-lasting mucoadhesive formulations
- Scalable platform: Pipeline opportunities in medical, veterinary, and consumer health markets
- Commercial momentum: Early revenues achieved, supported by high-margin business model
Kunde / Markt
PerioTrap serves health-conscious consumers seeking effective gum care as well as patients guided by dental professionals. Our primary entry point is the professional dental channel: dentists and hygienists recommend our products after cleanings, creating trust and driving adoption. From there, customers access our toothpaste and gel through pharmacies and online shops, ensuring availability in everyday routines. Over time, we target broader consumer segments who value microbiome-friendly oral care, while also addressing specialized needs in international and veterinary markets.
Team
Our team combines deep scientific expertise with strong business execution. PerioTrap was co-founded by Dr. Mirko Buchholz, a pharmacist with more than 25 years of experience in enzymology and drug discovery and the inventor of our core technology. The management is led by Pierre Tangermann, who brings expertise in biotech commercialization, fundraising, and strategic partnerships. The founders are complemented by an interdisciplinary team covering microbiology, analytics, formulation, regulatory affairs, quality management, and clinical operations. This broad capability base ensures that our patented technology is advanced with scientific rigor, translated into stable and effective formulations, and guided through regulatory pathways into scalable market-ready products.Join Us in Redefining Oral Health
PerioTrap is building the next generation of oral care – products that protect gums, preserve the microbiome, and support overall health. With our patented technology, trusted dental partnerships, and first products already in market, we are now entering the next growth phase. By participating in our current financing round, you can help bring microbiome-friendly oral care to millions worldwide – and share in the value we create.